Anti-Dimethyl (Lys9), Phospho (Ser10) Histone H3 [6HH3-2C5]

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Dimethyl (Lys9), Phospho (Ser10) Histone H3 [6HH3-2C5]

catalog :

152231

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3020

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-Dimethyl (Lys9), Phospho (Ser10) Histone H3 [6HH3-2C5]

Catalogue Number :

152231

Applications :

ELISA IF WB

Antigen/Gene or Protein Targets :

Histone H3 Dimethyl (Lys9)-Phospho (Ser10)

Reactivity :

Human and Mouse

Relevance :

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Host :

Mouse

Immunogen :

Ovalbumin conjugated synthetic peptide: AR[dimethyl-K][phospho- S]TGGKAPRKQL-(C) corresponding to aa 7-20 of Histone H3 (17 kDa). This sequence is conserved in a wide range of species.

Subclass :

IgG1 kappa

Research Area :

Cancer, Cell Signaling & Signal Transduction, DNA Damage and Repair, Epigenetics & Nuclear Signalling, Metabolism

Notes :

Available in 100ul unit as ascites.

more info or order :

Ximbio product webpage