Anti-dimethyl-Histone H3 (Lys14) [5HH3-2B10] | Ximbio 152230 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-dimethyl-Histone H3 (Lys14) [5HH3-2B10]

catalog :

152230

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3020

reactivity :

human, mouse

application :

western blot, ELISA

more info or order :

Ximbio product webpage

product information

Name :

Anti-dimethyl-Histone H3 (Lys14) [5HH3-2B10]

Catalogue Number :

152230

Applications :

ELISA WB

Antigen/Gene or Protein Targets :

Histone H3 dimethyl (K14)

Reactivity :

Human and Mouse

Relevance :

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Host :

Mouse

Immunogen :

Ovalbumin conjugated synthetic peptide: TARKSTGG[dimethyl-K] APR-(C) corresponding to aa 6-17 of Histone H3. This sequence is conserved in a wide range of species.

Subclass :

IgG1 kappa

Research Area :

Cancer, Cell Signaling & Signal Transduction, DNA Damage and Repair, Epigenetics & Nuclear Signalling, Metabolism

Notes :

Available in 100ul unit as ascites.

more info or order :

Ximbio product webpage