product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-Dimethyl Histone H3 (Lys9) [4HH3-2A12]
catalog :
152228
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4HH3-2A12
reactivity :
human
application :
western blot, ELISA, immunocytochemistry
more info or order :
Ximbio product webpage
product information
Name :
Anti-Dimethyl Histone H3 (Lys9) [4HH3-2A12]
Catalogue Number :
152228
Applications :
ELISA IF WB
Antigen/Gene or Protein Targets :
Histone H3 (Dimethyl-Lys9) (17 kDa).
Relevance :
The Monoclonal anti?dimethyl?Histone H3 (Lys9) antibody, clone 4HH3?2A12, has been validated for ELISA, Western Blot, immunofluorescence and immunoprecipitation. Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Histone H3 is the most extensively modified of the five histones and is an important protein in the emerging field of epigenetics, where its sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Di- and Tri-methylation of Lysine 9 are associated with repression and heterochromatin, while mono-methylation of K4 is associated with active genes.
Host :
Mouse
Immunogen :
Ovalbumin conjugated synthetic peptide (TAR[dimethyl?K]STGGKAPRC) corresponding to aa 6?17 of Histone H3. This sequence is conserved in a wide range of species.
Subclass :
IgG2a kappa
Research Area :
Cancer, Cell Signaling & Signal Transduction, DNA Damage and Repair, Epigenetics & Nuclear Signalling, Metabolism
Notes :
Available in 100ul unit as ascites. Recommended dilutions: 1/500?1/5000
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com