product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-FUS [1FU-1D2]
catalog :
152204
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2521
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
product information
Name :
Anti-FUS [1FU-1D2]
Catalogue Number :
152204
Applications :
ELISA IHC IF IP WB
Antigen/Gene or Protein Targets :
FUS / TLS
Reactivity :
Human
Relevance :
The Monoclonal anti?human FUS/TLS, clone 1FU?1D2, recognises human FUS/TLS. Reactivity to other species has not been tested. RNA-binding protein FUS/TLS (Fused in Sarcoma/Translocated in Sarcoma) is a member of the TET protein family that also includes the EWS protein, the TATA-binding protein (TBP)-associated factor (TAFII68/TAF15) and the Drosophila cabeza/SARF protein. FUS gene rearrangement has been implicated in the pathogenesis of both myxoid liposarcoma and low grade fibromyxoid sarcoma. Diseases associated with FUS include tremor, hereditary essential, 4 and amyotrophic lateral sclerosis 6, autosomal recessive, with or without frontotemporal dementia. Among its related pathways are Translational Control and Transcriptional misregulation in cancer.
Host :
Mouse
Immunogen :
Synthetic peptide (GPRDQGSRHDSEQDNSDC) coupled to ovalbumin. From aa 266 to aa 283
Subclass :
IgG1 kappa
Research Area :
Cancer, Epigenetics & Nuclear Signalling, Neurobiology
Notes :
Available in 100ul unit as ascites. Recommended dilutions: 1/500?1/5000
more info or order :
company information
Ximbio
enquiries@ximbio.com
ximbio.com