Anti-Frataxin [2FRA-1G2] | Ximbio 152203 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Frataxin [2FRA-1G2]

catalog :

152203

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2395

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-Frataxin [2FRA-1G2]

Catalogue Number :

152203

Applications :

ELISA IF WB

Antigen/Gene or Protein Targets :

Frataxin

Reactivity :

Human

Relevance :

The monoclonal anti-FRATAXIN antibody, clone 2FRA?1G2 recognises human Frataxin. Frataxin is localized to the mitochondrion. The function of frataxin is not entirely clear, but it seems to be involved in assembly of iron-sulfur clusters. It has been proposed to act as either an iron chaperone or an iron storage protein. Its mRNA is predominantly expressed in tissues with a high metabolic rate (including liver, kidney, brown fat and heart). Reduced expression of frataxin is the cause of Friedreich's ataxia (FRDA), a lethal neurodegenerative disease. An overexpression of frataxin in Drosophila has shown an increase in antioxidant capability, resistance to oxidative stress insults and longevity.

Host :

Mouse

Immunogen :

TrpE?Frataxin full length

Subclass :

IgG1 kappa

Research Area :

Cancer, Cell Type or Organelle Marker, Epigenetics & Nuclear Signalling, Metabolism, Neurobiology

Notes :

Available in 100ul unit as ascites. Recommended dilutions : 1/5000 for western blot 1/100?1/1000 for immunofluorescence

more info or order :

Ximbio product webpage