Anti-Esr2 [4ERß-2D7] | Ximbio 152198 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Esr2 [4ERß-2D7]

catalog :

152198

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2099

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-Esr2 [4ERß-2D7]

Catalogue Number :

152198

Applications :

ELISA IHC IF WB

Antigen/Gene or Protein Targets :

Estrogen receptor b (F region)

Reactivity :

Human and Mouse

Relevance :

The Monoclonal anti?ERß (F?region) Clone 4ERß?2D7 reacts on ERß from mouse and human origin. No cross?reactivity has been observed on ER alpha. It has been validated for ELISA, Western Blot (natural and recombinant proteines), Immunofluorescence and Immunohistochemistry. Estrogen receptors are activated by the hormone estrogen (17?-estradiol). Once activated by estrogen, the ER is able to translocate into the nucleus and acts as a a DNA-binding transcription factor. ERa and ERb regulate gene transcription by direct binding to estrogen-regulated elements (ERE) or indirectly by protein-protein interaction with transcription factor activator protein-1 (AP-1) and Sp1. Estrogens are important for mammary gland morphogenesis and differentiation.

Host :

Mouse

Immunogen :

CCSTEDSKSKEGSQNLQSQ (synthetic peptide derived from the Fregion of mouse ERß)

Subclass :

IgG1 kappa

Research Area :

Cancer, Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling, Neurobiology

Notes :

Available in 100ul unit as ascites,

more info or order :

Ximbio product webpage