Anti-ESR1 [ER-F3] | Ximbio 152195 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-ESR1 [ER-F3]

catalog :

152195

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2099

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation, ChIP-Seq

more info or order :

Ximbio product webpage

product information

Name :

Anti-ESR1 [ER-F3]

Catalogue Number :

152195

Applications :

ELISA IF IP WB ChIP-seq

Antigen/Gene or Protein Targets :

Estrogen receptor a (F region)

Reactivity :

Human

Relevance :

The Monoclonal anti?Human Estrogen Receptor a does not cross react with chicken. Other reactivities have not been evaluated. Estrogen receptors are activated by the hormone estrogen (17?-estradiol). Once activated by estrogen, the ER is able to translocate into the nucleus and acts as a a DNA-binding transcription factor. ERa and ERb regulate gene transcription by direct binding to estrogen-regulated elements (ERE) or indirectly by protein-protein interaction with transcription factor activator protein-1 (AP-1) and Sp1. Estrogens are important for mammary gland morphogenesis and differentiation.

Host :

Mouse

Immunogen :

SLQKYYITG-EAEGFPAVT (synthetic peptide corresponding to amino acids 578?595 of human ER alpha)

Subclass :

IgG1 kappa

Research Area :

Cancer, Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling, Neurobiology

Notes :

Available in 100ul unit as ascites. Recommended dilutions: 1/500?1/5000 For IP and Gel Shift: 1/10?1/20

more info or order :

Ximbio product webpage