Anti-E6 [2E-3F8] | Ximbio 152191 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-E6 [2E-3F8]

catalog :

152191

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2E-3F8

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-E6 [2E-3F8]

Catalogue Number :

152191

Applications :

ELISA IF WB

Antigen/Gene or Protein Targets :

E6 Papillomavirus Type16

Reactivity :

Virus

Relevance :

The E6 of human papillomavirus type 16 (HPV16) is a 158 aa protein expressed in transformed human cells after infection. E6 protein mediates the degradation of the cellular p53 tumour suppressor protein. It activates transcription of the telomerase gene and acts as a DNA binding protein with high affinity for four-way DNA junctions. In addition to p53, E6 interacts with a variety of cellular proteins, of which a significant number act at the transcriptional level. E6 is present in a large number of cervical carcinomas.

Host :

Mouse

Immunogen :

Human papillomavirus type 16 (HPV16) E6 fragment from K101 to R151 as a fusion protein.

Subclass :

IgG2a kappa

Research Area :

Cancer, Virology

Notes :

Available in 100ul unit as ascites.

more info or order :

Ximbio product webpage