product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-NR0B1 [1DA-2F4]
catalog :
152188
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1DA-2F4
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
more info or order :
product information
Name :
Anti-NR0B1 [1DA-2F4]
Catalogue Number :
152188
Applications :
ELISA IHC IF WB
Antigen/Gene or Protein Targets :
DAX-1(NROB1)
Relevance :
DAX?1 (NR0B1) is an unusual orphan member of the nuclear hormone receptor family. Duplications in Xp21, containing the DAX?1 gene, cause phenotypic sex reversal in XY individuals (DSS), while DAX?1 gene mutations are responsible for adrenal hypoplasia congenita (AHC), invariably associated with hypogonadotropic hypogonadism (HHG). DAX?1 functions as a negative regulator of steroid hormone production by repressing the expression of multiple genes involved in the steroidogenic pathway.
Host :
Mouse
Immunogen :
(C)GEDHPRQGSILYSLLTSSKQTHVAPAAPEAR
Subclass :
IgG1 kappa
Research Area :
Epigenetics & Nuclear Signalling
Notes :
Available in 100ul unit as ascites.
more info or order :
company information
Ximbio
enquiries@ximbio.com
ximbio.comreview
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