Anti-CSB [1CSB-1A11] | Ximbio 152185 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-CSB [1CSB-1A11]

catalog :

152185

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1443

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-CSB [1CSB-1A11]

Catalogue Number :

152185

Applications :

ELISA IF WB

Antigen/Gene or Protein Targets :

CSB (Cockayne syndrome B protein)

Reactivity :

Human

Relevance :

Monoclonal anti-CSB, clone 1CSB-1A11, has been validated for ELISA, Western Blot and Immunocytochemistry. Cockayne syndrome (CS), also called Neill-Dingwall syndrome, is a rare autosomal recessive neurodegenerative disorder characterized by growth failure, impaired development of the nervous system, abnormal sensitivity to sunlight (photosensitivity), eye disorders and premature aging. Mutations in the ERCC8 (also known as CSA) gene or the ERCC6 (also known as CSB) gene are the cause of Cockayne syndrome. Mutations in the ERCC6 gene mutation makes up ~70% of cases. The proteins made by these genes are involved in repairing damaged DNA via the transcription-coupled repair mechanism, particularly the DNA in active genes.

Host :

Mouse

Immunogen :

RYRDDGDEDYYKQRLRRWNK (Synthetic peptide corresponding to aa 451-470 of human CSB)

Subclass :

IgG1 kappa

Research Area :

DNA Damage and Repair, Epigenetics & Nuclear Signalling, Neurobiology

Notes :

Available in 100ul unit as ascites. Recommended dilutions: 1/500-1/5000

more info or order :

Ximbio product webpage