Anti-ACTA1 [1ACT-2D7] | Ximbio 152167 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-ACTA1 [1ACT-2D7]

catalog :

152167

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-ACTA1 [1ACT-2D7]

Catalogue Number :

152167

Applications :

IF WB

Antigen/Gene or Protein Targets :

Actin

Reactivity :

Human, Mouse and Rat

Relevance :

Clone 1ACT-2D7 recognises human Actin. Actin is a ubiquitous globular protein that is one of the most highly-conserved proteins known. It is found in two intrinsically flexible states; G-actin is the globular monomeric form, whereas F-actin forms helical polymers. Both have a role as a dynamic filament network. Actin has four major functions. Firstly, F-actin polymers form microfilaments - polar intracellular 'tracks' for kinesin motor proteins, allowing the transport of vesicles, organelles and other cargo. Actin is a component of the cytoskeleton and links to alpha-actinin, E-cadherin and beta-catenin at adherens junctions. This gives mechanical support to cells and attaches them to each other and the extracellular matrix. In muscle cells, actin-rich thin filaments associate with myosin-rich thick filaments to form actomyosin myofibrils. Using energy from the hydrolysis of ATP, myofibrils undergo cyclic shortening through actin-myosin head interactions, which represents the mechanics of muscle contraction. Finally, actin has a role in cell motility through polymerization and depolymerization of fibrils.

Host :

Mouse

Immunogen :

CYDEAGPSIVHRK

Subclass :

IgG2a kappa

Research Area :

Apoptosis and Programmed Cell Death, Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction

Notes :

Available in 100ul unit as ascites.

more info or order :

Ximbio product webpage