product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-Cytochrome P450 4V2 [M29-P3B10]
catalog :
152159
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1577
reactivity :
human
application :
western blot, ELISA, immunohistochemistry
more info or order :
Ximbio product webpage
product information
Name :
Anti-Cytochrome P450 4V2 [M29-P3B10]
Catalogue Number :
152159
Applications :
ELISA IHC WB
Antigen/Gene or Protein Targets :
Cytochrome P450, family 4, subfamily V, polypeptide 2 (CYP4V2)
Synonyms :
Cytochrome P450; Family 4; Subfamily V; Polypeptide 2; Docosahexaenoic Acid Omega-Hydroxylase CYP4V2; CYP4AH1; BCD
Reactivity :
Human
Relevance :
Cytochrome P450, family 4, subfamily V, polypeptide 2 (CYP4V2) encodes a member of the cytochrome P450 superfamily of enzymes that are a group of heme-thiolate monooxygenases. Cytochromes P450 catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP4V2 catalyzes the omega-hydroxylation of medium-chain saturated fatty acids such as laurate, myristate and palmitate in an NADPH-dependent pathway. CYP4V2 may have a role in fatty acid and steroid metabolism in the eye and its mutations are associated with Bietti's crystalline dystrophy (BCD) and retinitis pigmentosas.
Host :
Mouse
Immunogen :
Peptide sequence – KREELGLEGQ (amino acids 495 – 504)
Subclass :
IgG1 kappa
Positive Control :
ELISA- Peptide immunogen; Western Blot- Human liver microsomes; IHC- Human liver
Myeloma Used :
P3X63Ag8.653
Recommended Growing Conditions :
Dulbecco’s media containing 20% Fetal Bovine serum (DH20) prepared as follows (for final volume of 300ml: 237ml DMEM + 60 ml Fetal Bovine Serum plus 3ml L-Glutamine + 3ml of Penicillin -Streptomycin.
Strain :
Balb/c
Research Area :
Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com