product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-Cytochrome P450 8B1 [M15-P3B7]
catalog :
152155
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1577
reactivity :
human, rat
application :
western blot, ELISA, immunohistochemistry
more info or order :
product information
Name :
Anti-Cytochrome P450 8B1 [M15-P3B7]
Catalogue Number :
152155
Applications :
ELISA IHC WB
Antigen/Gene or Protein Targets :
Cytochrome P450, family 8, subfamily B, polypeptide 1 (CYP8B1)
Reactivity :
Human and Rat
Relevance :
Implicated in hepatocellular carcinoma. CYP8B1 is upregulated in primary and metaststic colorectal tumours compared to normal colon mucosa.
Host :
Mouse
Immunogen :
Peptide sequence– QPSHDVRFR (amino acids 486 – 494)
Subclass :
IgG2b
Positive Control :
ELISA- Peptide immunogen; Western Blot- Human liver microsomes; IHC- Human liver
Myeloma Used :
P3X63Ag8.653
Recommended Growing Conditions :
Dulbecco’s media containing 20% Fetal Bovine serum (DH20) prepared as follows (for final volume of 300ml: 237ml DMEM plus 60 ml Fetal Bovine Serum plus 3ml L-Glutamine).
Strain :
Balb/c
Research Area :
Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism
Notes :
This antibody was applied in a poster presented at the 2015 NCRI conference: http://abstracts.ncri.org.uk/?s=oxysterol&year_published=2015
more info or order :
company information
Ximbio
enquiries@ximbio.com
ximbio.com