product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-HHV-8 LNA-1 [LN53]
catalog :
152152
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
4961527
reactivity :
Kaposi's sarcoma-associated herpesvirus - Human herpesvirus 8
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, FACS
more info or order :
product information
Name :
Anti-HHV-8 LNA-1 [LN53]
Catalogue Number :
152152
Applications :
ELISA FACS IHC IP WB
Antigen/Gene or Protein Targets :
Latent nuclear antigen 1 (LNA-1; ORF73) of HHV-8
Synonyms :
ORF-73 of human herpesvirus 8 or HHV-8 positive cells
Reactivity :
Virus
Relevance :
Human herpesvirus-8 has been found to be associated with three different diseases observed in AIDS patients; Kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. To date there is much evidence to support a direct role for HHV-8 in Kaposi's sarcoma. HHV-8 encodes a latent nuclear antigen (LNA-1) which is the product of the viral gene orf 73. LNA-1 is recognized by most infected patient sera and is the basis of current immunofluorescence assays used in epidemiological studies of HHV-8 infection.
Host :
Rat
Immunogen :
Recombinant protein corresponding to the latent nuclear antigen-1 molecule of HHV-8
Subclass :
IgG2c
Research Area :
Virology
Notes :
LN53 recognizes the epitope EQEQE. The LN53 epitope is contained within the repetitive region of LNA-1, resulting in 23 copies of the LN53 epitope in full-length LNA-1. LN53 reacts to Human herpesvirus 8.
more info or order :
company information
Ximbio
enquiries@ximbio.com
ximbio.com