Anti-Phospho Amyloid-ß (Ser8) [1E4E11] | Ximbio 152133 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Phospho Amyloid-ß (Ser8) [1E4E11]

catalog :

152133

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

334

reactivity :

human

application :

western blot, immunohistochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-Phospho Amyloid-ß (Ser8) [1E4E11]

Catalogue Number :

152133

Applications :

IHC WB

Antigen/Gene or Protein Targets :

Amyloid-ß

Reactivity :

Human

Relevance :

The progressive accumulation of extracellular amyloid plaques in the brain is a common hallmark of Alzheimer’s disease (AD). We recently identified a novel species of A? phosphorylated at serine residue 8 with increased propensity to form toxic aggregates as compared to non-phosphorylated species. Phosphorylated A? could represent an important species in the formation and stabilization of neurotoxic aggregates, and might be targeted for AD therapy and diagnosis.

Host :

Mouse

Immunogen :

Phosphorylated Amyloid-ß at Serine 8

Research Area :

Neurobiology

more info or order :

Ximbio product webpage