Anti-Cytochrome P450 2R1 [M26-P6H1] | Ximbio 152121 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Cytochrome P450 2R1 [M26-P6H1]

catalog :

152121

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1577

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-Cytochrome P450 2R1 [M26-P6H1]

Catalogue Number :

152121

Applications :

ELISA IHC WB

Antigen/Gene or Protein Targets :

CYP2R1, Cytochrome P450, family 2, subfamily R, polypeptide 1.

Reactivity :

Human and Mouse

Relevance :

Cytochrome P450 2R1 (CYP2R1) encodes a member of the cytochrome P450 superfamily of enzymes that are a group of heme-thiolate monooxygenases. Cytochromes P450 catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP2R1 expressed in the liver is a microsomal vitamin D hydroxylase that converts vitamin D into 25-hydroxyvitamin D (calcidiol), the major circulatory form of the vitamin.

Host :

Mouse

Immunogen :

Ovalbumin-conjugated synthetic peptide QPYLICAERR (C-terminal sequence).

Positive Control :

IHC: formalin-fixed, paraffin-embedded human kidney sections. WB: pooled liver microsomes.

Myeloma Used :

P3X63Ag8.653

Recommended Growing Conditions :

Dulbecco’s media containing 20% Fetal Bovine serum (DH20) prepared as follows (for final volume of 300ml: 237ml DMEM plus 60 ml Fetal Bovine Serum plus 3ml L-Glutamine).

Research Area :

Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism

Notes :

This antibody was applied in a poster presented at the 2015 NCRI conference: http://abstracts.ncri.org.uk/?s=oxysterol&year_published=2015

more info or order :

Ximbio product webpage