product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-HDAC3 [3G6]
catalog :
152099
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
8841
reactivity :
human, mouse, cow
application :
western blot, immunoprecipitation
more info or order :
Ximbio product webpage
product information
Name :
Anti-HDAC3 [3G6]
Catalogue Number :
152099
Applications :
IP WB
Antigen/Gene or Protein Targets :
HDAC3
Reactivity :
Bovine, Hamster, Human and Mouse
Relevance :
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. HDAC3 is regarded as a potential tumor suppressor gene.
Host :
Mouse
Immunogen :
peptide corresponding to human HDAC3
Subclass :
IgG2a
Molecular Weight (kDa) :
50
Research Area :
Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling, Metabolism
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com