Anti-Histone H3 [1B1-B2] | Ximbio 152093 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Histone H3 [1B1-B2]

catalog :

152093

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3020

reactivity :

human, mouse

application :

western blot, chromatin immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-Histone H3 [1B1-B2]

Catalogue Number :

152093

Applications :

ChIP WB

Antigen/Gene or Protein Targets :

Human histone H3

Reactivity :

Human, Mouse, Saccharomyces, Schizosaccharomyces pombe, Saccharomyces cerevisiae and Saccharomyces frugiperda

Relevance :

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Histone proteins are highly post-translationally modified, and histone H3 is the most extensively modified of the five histones. Histone H3 sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Di- and tri-methylation of histone H3 are gene silencing marks, while removal of these marks by the demethylase genes Jmjd1a and Jmjd2c leads to gene activation.

Host :

Mouse

Immunogen :

Linear peptide corresponding to the C-terminus of human histone H3.

Subclass :

IgG

Research Area :

Cell Structure and Motility, Epigenetics & Nuclear Signalling

more info or order :

Ximbio product webpage