Anti-APC [c-APC 28.9] | Ximbio 152092 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-APC [c-APC 28.9]

catalog :

152092

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

324

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-APC [c-APC 28.9]

Catalogue Number :

152092

Applications :

IHC IF IP WB

Antigen/Gene or Protein Targets :

APC

Reactivity :

Human

Relevance :

The adenomatous polyposis coli tumor suppressor gene is mutated (often deletion of the C-terminal portion of APC) in the inherited disease, familial adenomatous polyposis (FAP), and over 80% of colorectal cancers. C-APC 28.8 can be used for APC expression and detection of APC mutations. Clone c-APC 28.9 is useful for the detection of APC expression and detection of mutations. This antibody has been used routinely for Western blotting on colon cell line HCT116 extract which expresses full-length APC.

Host :

Mouse

Immunogen :

human APC C-terminal fusion with MBP (maltose binding protein)

Subclass :

IgG1 kappa

Positive Control :

Colon cell line HCT116

Research Area :

Cancer, Cardiovascular, Cell Cycle, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling, Neurobiology, Stem Cell Biology

more info or order :

Ximbio product webpage