Anti-Alpha Tubulin [DM1A] | Ximbio 151933 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Alpha Tubulin [DM1A]

catalog :

151933

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7846

reactivity :

human, mouse, rat, dog, chicken, cow

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-Alpha Tubulin [DM1A]

Catalogue Number :

151933

Applications :

FACS IHC IF IP WB

Antigen/Gene or Protein Targets :

TUBA1A

Reactivity :

Bovine, Chicken, Dog, Drosophila, Hamster, Human, Guinea Pig, Mouse, Pig, Primate, Rat, Rabbit and Xenopus laevis

Relevance :

The cytoskeleton consists of three major types of cytosolic fibers: microtubules (consisting of tubulin), microfilaments (actin filaments), and intermediate filaments. Tubulin is a globular dimeric protein of alpha/beta chains and it has five distinct forms labeled as -a, -b,-g, -d and -e tubulin. a/b tubulins generates heterodimers which multimerize to form microtubule filaments. Several b tubulin isoforms such as b1, b2, b3, b4, b5, b6 , b8 etc have been identified among which b1/b4 are present in cytosol and b2 is present in nuclei/nucleoplasm. d/e tubulins are associated with centrosomes, whereas the g tubulin forms the gammasome, which is required for nucleating microtubule filaments at centrosomes. Several cellular movements are mediated by microtubule action which includes the beating of cilia and flagella, cytoplasmic transport of membrane vesicles, chromosome alignment during meiosis/mitosis, nerve-cell axon migration etc and these movements result from competitive microtubule polymerization/depolymerization or through the actions of microtubule motor proteins.

Host :

Mouse

Immunogen :

Native chicken brain microtubules

Subclass :

IgG1 kappa

Molecular Weight (kDa) :

Research Area :

Cell Type or Organelle Marker, Cell Signaling & Signal Transduction

more info or order :

Ximbio product webpage