Anti-POT1 [M1-P1H5] | Ximbio 151875 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-POT1 [M1-P1H5]

catalog :

151875

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

25913

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-POT1 [M1-P1H5]

Catalogue Number :

151875

Applications :

ELISA IF WB

Antigen/Gene or Protein Targets :

Protection of telomeres 1 (POT1)

Reactivity :

Human

Relevance :

POT1 (protection of telomeres 1) is part of the telomerase ribonucleotide (RNP) complex, which stabilises chromosomes by controlling telomere elongation. POT1 is a component of the double-stranded telomeric DNA-binding TRF1 complex which cis-inhibits telomerase. POT1 localization on telomeres diminishes in the absence of single-stranded DNA.

Host :

Mouse

Immunogen :

Peptide sequence - IPASEVLMDD

Subclass :

IgG1 kappa

Positive Control :

ELISA- Peptide immunogenWestern Blot- Hela cell extract (nuclear fraction)IF- Hela Cells

Recommended Growing Conditions :

Dulbecco’s media containing 20% Fetal Bovine serum (DH20) prepared as follows (for final volume of 300ml: 237ml DMEM + 60 ml Fetal Bovine Serum plus 3ml L-Glutamine + 3ml of Penicillin -Streptomycin.

Strain :

Balb/c

Research Area :

Cancer, Cell Cycle, Epigenetics & Nuclear Signalling

Notes :

BLAST analysis of immunogen peptide has revealed 100% identity to mouse and rat

more info or order :

Ximbio product webpage