Anti-Cytochrome P450 3A4 [F24 P2 B10] | Ximbio 151862 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Cytochrome P450 3A4 [F24 P2 B10]

catalog :

151862

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1576

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-Cytochrome P450 3A4 [F24 P2 B10]

Catalogue Number :

151862

Applications :

ELISA IHC WB

Antigen/Gene or Protein Targets :

CYP3A4 & CYP3A5 Cytochrome P450 3A4 (EC 1.14.13.67) (Quinine 3-monooxigenase)

Reactivity :

Human

Relevance :

Cytochrome P450 3A4 (CYP3A4) encodes a member of the cytochrome P450 superfamily of enzymes that are a group of heme-thiolate monooxygenases. Cytochromes P450 catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP3A4 expressed mainly in the liver and intestine oxidizes xebiotics that are then removed from the body.

Host :

Mouse

Immunogen :

Ovalbumin-conjugated synthetic peptide ESRDGTVSGA

Subclass :

IgG1 kappa

Positive Control :

IHC: formalin-fixed, paraffin-embedded prostate cancer sections. Western blot: recombinant P450 (shown below @ 0.5 pmol per lane). Negative control: Gentest Cat. No M101b.

Myeloma Used :

P3X63Ag8.653

Recommended Growing Conditions :

Dulbecco’s media containing 20% Fetal Bovine serum (DH20) prepared as follows (for final volume of 300ml: 237ml DMEM + 60 ml Fetal Bovine Serum plus 3ml L-Glutamine + 3ml of Penicillin -Streptomycin.

Strain :

Balb/c

Research Area :

Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism

more info or order :

Ximbio product webpage