product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-RSV G Glycoprotein [11-2-D2]
catalog :
151859
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
961
reactivity :
human
application :
western blot, ELISA, immunocytochemistry
more info or order :
product information
Name :
Anti-RSV G Glycoprotein [11-2-D2]
Catalogue Number :
151859
Applications :
ELISA IF Fn WB
Antigen/Gene or Protein Targets :
Human Respiratory Syncytial (RS) virus G glycoprotein
Synonyms :
GP90
Reactivity :
Virus
Relevance :
Human Respiratory Syncytial Virus (RSV) is a major cause of lower respiratory tract illness and is the chief cause of hospitalization for respiratory tract illness in young children. The glycoprotein G (also named GP90) is located on the surface of viral envelope, its function is to attach to host cell receptors. It has high content (90%) of carbohydrate. To our knowledge, this is the only G specific antibody reported to induce in vitro antibody-dependent enhancement of macrophage cells (Clin Diagn Lab Immunol. 1996 May;3(3):280-6).
Host :
Mouse
Immunogen :
Gradient-purified RSF-44 virus (subgroup A) UV inactivated for 20 minutes at 20C
Subclass :
IgG2a kappa
Positive Control :
WB: Ag: gradient-purified RS virus (see figure). IF: staining of RSA-2 infected BSC-1 cells
Myeloma Used :
P3X63Ag8.653
Recommended Growing Conditions :
Dulbecco’s media containing 20% Fetal Bovine serum (DH20) prepared as follows (for final volume of 300ml: 237ml DMEM plus 60 ml Fetal Bovine Serum plus 3ml L-Glutamine).
Strain :
Balb/c
Research Area :
Virology
Notes :
Antibody reactive with Glycoprotein G of subgroup B
more info or order :
company information
Ximbio
enquiries@ximbio.com
ximbio.com