product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-RSV Nucleoprotein VP41 [4-18]
catalog :
151852
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4-18
reactivity :
human
application :
western blot, ELISA, immunocytochemistry
more info or order :
Ximbio product webpage
product information
Name :
Anti-RSV Nucleoprotein VP41 [4-18]
Catalogue Number :
151852
Applications :
ELISA IF WB
Antigen/Gene or Protein Targets :
Human Respiratory Syncytial Virus (RSV) nucleoprotein VPN41
Reactivity :
Virus
Relevance :
Human Respiratory Syncytial Virus (RSV) is a major cause of lower respiratory tract illness and is the chief cause of hospitalization for respiratory tract illness in young children. There are two RS virus subgroups, A and B. The A and B subgroups circulate concurrently with subgroup A usually dominating. This antibody is useful for the diagnosis of RS virus subgroup A and B infections, since the nucleoprotein is very abundant within infected cells, which makes virus detection assays highly sensitive.The nucleoprotein is located in the nucleocapsid of the virion; it is abundant and forms a tight complex with virus genomic RNA. Anti-Nucleoprotein VP41 [RSV 4-18] reacts with both human RS virus Subgroups A and B.
Host :
Mouse
Immunogen :
Gradient-purified RSN-2 virus (subgroup B) treated with 0.1% SDS at 100°C for 2 mins.
Subclass :
IgG2a
Positive Control :
Immunoblot: Gradient-purified RSN-2 virus 5ug per lane. Lanes 1 and 2.First antibodies: Line1 RSV convalescent human sera. Lane 2: 4-18 antibody. Indirect immunofluorescence: staining of RSN-2 infected BSC-1 cells
Myeloma Used :
P3X63Ag8.653
Recommended Growing Conditions :
Dulbecco’s media containing 20% Fetal Bovine serum (DH20) prepared as follows (for final volume of 300ml: 237ml DMEM plus 60 ml Fetal Bovine Serum plus 3ml L-Glutamine).
Strain :
Balb/c
Research Area :
Virology
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com