Anti-ANO5 [5F7] | Ximbio 151849 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-ANO5 [5F7]

catalog :

151849

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

203859

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-ANO5 [5F7]

Catalogue Number :

151849

Applications :

IF WB

Antigen/Gene or Protein Targets :

Anoctamin 5

Reactivity :

Human, Mouse and Rat

Relevance :

Antibody to muscular dystrophy gene. Relevant for anoctamin 5 linked diseases - muscular dystrophy, GDD1, dysferlinopathy. Antibody is of use for diagnostic and research purposes on anoctamin 5 and other anoctamins. The antibody also has relevance in research in cell membrane repair, membrane trafficking and chloride channels.

Host :

Mouse

Immunogen :

Sythetic peptide, C-Terminal. "CKREKLMTIKILHDFE

Subclass :

IgM

Positive Control :

C2C12, skeletal muscle

Molecular Weight (kDa) :

Myeloma Used :

Sp2/0-Ag14

Recommended Growing Conditions :

DMEM + antibiotic + 10% FCS

Research Area :

Cardiovascular, Cell Signaling & Signal Transduction

Notes :

Molecular Weight: The protein has an expected molecular mass of ~107kDa. However, it is rarely detected using this antibody in muscle tissue. By western blot using lysates prepared from C2C12 cells (wt), RD and fibroblasts 3 bands are detected; 37 KDa, 55kDa and the expected molecular mass. In the Aceview database (http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?db=human&term=ano5&submit=Go) there is evidence from clones of a short C-terminal isoform. This is likely the small isoform detected in control muscle.

more info or order :

Ximbio product webpage