product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-FANCM [CV5.1]
catalog :
151822
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
57697
reactivity :
human
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
product information
Name :
Anti-FANCM [CV5.1]
Catalogue Number :
151822
Applications :
IF IP WB
Antigen/Gene or Protein Targets :
Human FANCM (Fanconi anemia, complementation group M)
Synonyms :
Fanconi Anemia Complementation Group M; KIAA1596; Fanconi Anemia-Associated Polypeptide Of 250 Kda; ATP-Dependent RNA Helicase FANCM; Protein Hef Ortholog; FAAP250
Reactivity :
Human
Relevance :
Fanconi anemia, complementation group M. Fanconi anemia-associated polypeptide of 250 kDa. ATPase required for FANCD2 ubiquitination, a key reaction in DNA repair. Binds to ssDNA but not to dsDNA. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions.
Host :
Mouse
Immunogen :
His-tagged denatured FANCM (aa 1507-1679) made in E.coli
Subclass :
IgG1 kappa
Positive Control :
293 cell extract
Research Area :
DNA Damage and Repair, Epigenetics & Nuclear Signalling
Notes :
Suggested Dilutions: WB - 1:1000, IP - 2-4ug/ml lysate, IF - 1:100 Other species were not tested but there is high sequence conservation.
more info or order :
company information
Ximbio
enquiries@ximbio.com
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