Anti-PDGFR alpha [PDGFR-H7A] | Ximbio 151787 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-PDGFR alpha [PDGFR-H7A]

catalog :

151787

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4916

reactivity :

human

application :

immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-PDGFR alpha [PDGFR-H7A]

Catalogue Number :

151787

Applications :

Antigen/Gene or Protein Targets :

PDGFR alpha, platelet-derived growth factor receptor, alpha polypeptide.

Reactivity :

Human

Relevance :

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Host :

Mouse

Immunogen :

Recombinant protein corresponding to amino acids 1 to 78 of human PDGFRA

Subclass :

IgG1

Positive Control :

Human Hela cell line

Myeloma Used :

NS0

Recommended Growing Conditions :

RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT

Research Area :

Cancer

more info or order :

Ximbio product webpage