Anti-FMIP [F6D/11] | Ximbio 151786 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-FMIP [F6D/11]

catalog :

151786

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8563

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-FMIP [F6D/11]

Catalogue Number :

151786

Applications :

ELISA IHC WB

Antigen/Gene or Protein Targets :

Fms interacting protein (FMIP)

Reactivity :

Human

Relevance :

Fms interacting protein (FMIP) is a substrate, as well as a binding partner, of Fms tyrosine kinase. FMIP is a ubiquitous nuclear/cytoplasm shuttling protein with a leucine zipper. The overexpression of FMIP in myeloid progenitor cells alters the macrophage colony stimulating factor (M-CSF)-mediated macrophage differentiation. These cells differentiate into the granulocytic lineage rather than into the macrophage lineage. Furthermore, it has been shown that FMIP is one of the major molecules phosphorylated via the insulin-mediated signaling pathway in a preadipocyte cell line, 3T3-L1 cells, suggesting that FMIP may play a role in adipocyte differentiation.

Host :

Mouse

Immunogen :

C-terminus of the human FMIP protein as a glutathione-S-transferase (GST) fusion protein

Subclass :

IgG1

Myeloma Used :

P3/NS1/1-Ag4.1

Recommended Growing Conditions :

RPMI 1640 supplemented with 10% FBS, L-glutamine, Ultroser G and HAT. Please note that they have not been weaned off HAT and will not grow without it.

Research Area :

Cell Signaling & Signal Transduction, Cell Structure and Motility, Immunology

more info or order :

Ximbio product webpage