Anti-CD70 [TAN 1-7] | Ximbio 151721 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-CD70 [TAN 1-7]

catalog :

151721

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

21948

reactivity :

mouse

application :

ELISA, immunocytochemistry, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-CD70 [TAN 1-7]

Catalogue Number :

151721

Applications :

ELISA FACS IF Fn

Antigen/Gene or Protein Targets :

CD70

Synonyms :

CD70 Molecule; Tumor Necrosis Factor Ligand Superfamily Member 7; CD27 Ligand; CD27LG; TNFSF7; CD27L; Tumor Necrosis Factor Ligand 8A; Surface Antigen CD70; Ki-24 Antigen; CD70 Antigen; TNLG8A

Reactivity :

Mouse

Relevance :

CD70 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.

Host :

Rat

Immunogen :

Recombinant mouse CD70 (extracellular domain, aa residues 41-195)

Subclass :

IgG2a

Positive Control :

Activated dendritic cells

Myeloma Used :

NS0

Recommended Growing Conditions :

RPMI + 10%FCS+ Penicillin-Streptomycin

Research Area :

Apoptosis and Programmed Cell Death, Cancer, Immunology, Stem Cell Biology

Notes :

This antibody is a non-depleting mAb that blocks the CD70-CD27 interaction. Suggested Dilutions: 1-10mg/ml

more info or order :

Ximbio product webpage