product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-MTBP [2C1E11]
catalog :
151708
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
27085
reactivity :
human
application :
western blot
more info or order :
Ximbio product webpage
product information
Name :
Anti-MTBP [2C1E11]
Catalogue Number :
151708
Applications :
WB
Antigen/Gene or Protein Targets :
MTBP
Synonyms :
MDM2 Binding Protein, MDM2 (Mouse Double Minute 2)-Binding Protein, Mdm2, Transformed 3T3 Cell Double Minute 2, P53 Binding Protein (Mouse) Binding Protein, Mdm2, Transformed 3T3 Cell Double Minute 2, P53 Binding Protein Binding Protein, MDM2BP, HMTBP
Reactivity :
Human
Relevance :
MTBP is an MDM2 binding protein that alters p53/MDM2 homeostasis and may contribute to metastatic suppression. Recent studies have demonstrated that loss of MTBP expression in samples that are p53 positive and have low MDM2 is significantly associated with reduced patient survival in Squamous cell carcinoma of the head and neck (SCCHN).
Host :
Mouse
Immunogen :
Recombinant full-length human MTBP
Subclass :
IgG1
Research Area :
Cancer, Cell Cycle, Epigenetics & Nuclear Signalling
Notes :
Clone also known as 14 or T14.
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com