product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-cROS [4-6G]
catalog :
151666
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6098
reactivity :
human
application :
western blot, immunocytochemistry, immunoprecipitation, FACS
more info or order :
Ximbio product webpage
product information
Name :
Anti-cROS [4-6G]
Catalogue Number :
151666
Applications :
FACS IF IP Fn WB
Antigen/Gene or Protein Targets :
cROS
Reactivity :
Human
Relevance :
c-ROS is a proto-oncogene tyrosine kinase, that is highly-expressed in a variety of tumour cell lines and belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. It is a type I integral membrane protein and may function as a growth or differentiation factor receptor. The c-ROS gene promoter region has been identified and characterized and it has been shown that the ectopic expression of c-ROS in tumors is tied to hypomethylation of a CpG island in the c-ROS promoter.
Host :
Mouse
Immunogen :
Extracellular portion of ROS amino acid 1-285 fused to Fc, transiently expressed in 293 cells and purified using PtnA column chromatography.
Subclass :
IgG1
Positive Control :
Cells transiently expressing human cROS, mouse cells expressing human cROS
Myeloma Used :
Sp2/0-Ag14
Recommended Growing Conditions :
DMEM + 20% FCS low IgG
Research Area :
Cancer, Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com