Anti-Integrin aV?6 [Av?6 62ow.17] | Ximbio 151623 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Integrin aV?6 [Av?6 62ow.17]

catalog :

151623

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

3655

reactivity :

human

application :

western blot, immunohistochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-Integrin aV?6 [Av?6 62ow.17]

Catalogue Number :

151623

Applications :

IHC WB

Antigen/Gene or Protein Targets :

Integrin avß6

Reactivity :

Human

Relevance :

Alpha-v beta-6 is upregulated on cancers and during tissue remodelling but is weak absent on resting adult tissues. It promotes invasion and correlates with poor survival. It is likely to be good therapeutic target.

Host :

Rat

Immunogen :

Mouse fibroblasts retrovirally infected with cDNA to human beta6 (3T3?6.19). Cells expressed a mouse/human av?6 chimera.

Subclass :

IgG1

Positive Control :

BT20 breast carcinoma, original immunogen.

Recommended Growing Conditions :

DMEM containing glucose(4.5g/litre), bicarbonate(3.7g/litre), glutamine (4 x 10-3 M), penicillin(50U/ml), streptomycin(50ug/ml)and neomycin(100ug/ml). Also straight DMEM or RPMI 1640 with 3% FCS.

Research Area :

Cell Structure and Motility

Notes :

Does not recognise mouse av?6

more info or order :

Ximbio product webpage