Anti-MMP3 [1B4] | Ximbio 151620 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-MMP3 [1B4]

catalog :

151620

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4314

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-MMP3 [1B4]

Catalogue Number :

151620

Applications :

ELISA IHC IF IP WB

Antigen/Gene or Protein Targets :

Human matrix metalloproteinase 3 (MMP-3)

Reactivity :

Human

Relevance :

Human matrix metalloproteinase 3 (MMP-3) is a member of the matrix metalloproteinases (MMP) family that are peptidases involved in the breakdown of extracellular matrix proteins. MMP-3 degrades fibronectin, laminin, gelatins of type I, III, IV, and V; collagen of type II, III, IV, X, and IX, and proteoglycans. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling. The enzyme is also thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.

Host :

Mouse

Immunogen :

Ovalbumin-conjugated synthetic peptide; CKSLRKLEPELH

Subclass :

IgG1

Positive Control :

IHC: formalin-fixed, paraffin-embedded lung containing intra-alveolar macrophageswestern blot: rhMMP-3, 400 ng per lane

Myeloma Used :

P3X63Ag8.653

Strain :

Balb/c

Research Area :

Adhesion, Cancer, Cardiovascular, Epigenetics & Nuclear Signalling

Notes :

Western blot: not reactive with MMP-1, MMP-2, MMP-9

more info or order :

Ximbio product webpage