Anti-CLEC2 [17D9] | Ximbio 151581 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-CLEC2 [17D9]

catalog :

151581

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

52614

reactivity :

mouse

application :

western blot, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-CLEC2 [17D9]

Catalogue Number :

151581

Applications :

FACS WB

Antigen/Gene or Protein Targets :

Ctype lectin-like receptor (CLEC2)

Reactivity :

Mouse

Relevance :

CLEC-2 belongs to a sub-family of C-type lectin receptors that signal through Syk via a single YxxL motif (hemITAM). This antibody can be used as a selective agonist of CLEC-2 and also to study its expression pattern.

Host :

Rat

Immunogen :

RBL-2H3 cells stably expressing HA-tagged mouse CLEC-2

Subclass :

IgG2b

Myeloma Used :

Y3.AG.1.2.3

Recommended Growing Conditions :

RPMI + 10% FCS, 2-Mercaptoethanol and antibiotics

Research Area :

Cardiovascular, Immunology

Notes :

Recommended Concentrations: 10ug/ml for FACS, 50ug/ml for agonistic activity, 2ug/ml for Western. FACS data (see figure): : B3Z cells expressing mCLEC-2-HA-IRES-GFP were mixed with parental B3Z cells (GFP negatives) and stained either with anti-HA or anti-CLEC-2-biotinylated (17D9)(5µg/ml) followed by Streptavidin-PE.

more info or order :

Ximbio product webpage