Anti-Factor VIII [RFF-VIII:c/8] | Ximbio 151529 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Factor VIII [RFF-VIII:c/8]

catalog :

151529

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3054

reactivity :

human

application :

western blot, immunocytochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-Factor VIII [RFF-VIII:c/8]

Catalogue Number :

151529

Applications :

IF Fn WB

Antigen/Gene or Protein Targets :

Factor VIII

Reactivity :

Human

Relevance :

The commonest severe congenital bleeding disorder in all races is haemophilia A. The characteristic defect is a lack of coagulation factor VIII:C. Factor VIII:C is a glycoprotein that functions as a cofactor for factor IXa which, in the presence of calcium and phospholipids, converts factor X to the activated form Xa. This antibody binds to human FVIII:C heavy chain and inhibits its function.

Host :

Mouse

Immunogen :

Purified human factor VIII

Subclass :

IgG1 kappa

Myeloma Used :

P3/NS1/1-Ag4.1

Recommended Growing Conditions :

RPMI + 10% FCS; non-adherent; subculture every 2-3 days; split 1:5

Research Area :

Cardiovascular

more info or order :

Ximbio product webpage