Anti-von Willebrand Factor [RFF-VIII:R/2] | Ximbio 151527 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-von Willebrand Factor [RFF-VIII:R/2]

catalog :

151527

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

RFF-VIII:R/2

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS, radioimmunoassay

more info or order :

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product information

Name :

Anti-von Willebrand Factor [RFF-VIII:R/2]

Catalogue Number :

151527

Applications :

ELISA FACS IHC IF IP Fn RIA WB

Antigen/Gene or Protein Targets :

Von Willebrand factor (VWF)

Reactivity :

Primate

Relevance :

The monoclonal antibody RFF-VIII:R/1 specifically binds to human factor VIII related antigen (VIII:RAg) in plasma and in vascular endothelial cells but has no reactivity with factor VIII procoagulant antigen (VIII:cAg). This antibody is a potent inhibitor of von Willebrand factor activity in that it can totally neutralise risocetin-induced aggregation of platelet rich plasma and inhibit platelet adhesion at high flow rates. RFF-VIII:R/1 can be used in a one-stage, fluid phase immunoradiometric assay that can detect VIII:RAg. This monoclonal antibody binds to human von Willebrand factor (VW) and inhibits it's binding to platelets. Very similar in characteristics to RFF-VIII:R/2

Host :

Mouse

Immunogen :

Purified human Factor VIII-VWF complex

Subclass :

IgG1 kappa

Myeloma Used :

P3/NS1/1-Ag4.1

Recommended Growing Conditions :

RPMI + 10% FCS; non-adherent; subculture every 2-3 days; split 1:5

Research Area :

Cardiovascular, Stem Cell Biology

Notes :

ELISA 1:100-1:2000 Immunohistochemistry 1:10-1:2000 Immunohistochemistry-Frozen 1:25-1:100 Protein Array 1:100-1:2000 Radioimmunoassay 1:100-1:2000

more info or order :

Ximbio product webpage