Anti-HPV16 E1/E4 [TVG 401] | Ximbio 151522 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-HPV16 E1/E4 [TVG 401]

catalog :

151522

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5627

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-HPV16 E1/E4 [TVG 401]

Catalogue Number :

151522

Applications :

ELISA IHC WB

Antigen/Gene or Protein Targets :

Human Papilloma Virus 16 early proteins 1 and 4 (HPV16 E1/E4).

Reactivity :

Human papilloma virus

Relevance :

The human papilloma virus (HPV) family of DNA tumour viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. E1 and E2 are proteins involved in the regulation of viral DNA replication. The monoclonal antibodies TVG 401,TVG 402 and TVG 403 represent the first against HPV16 E1/ E4 and should complement those already available to E7 and L1 for the screening of frozen sections of clinical biopsies and will be of value in monitoring the progress of HPV infection from benign lesions to invasive cancer.

Host :

Mouse

Immunogen :

Antigen for hybridoma production was expressed as a b galactosidase fusion protein using the pEX expression system and was consequently cleaved to release the E1/ E4 polypeptide.

Subclass :

IgG1

Molecular Weight (kDa) :

Myeloma Used :

NS0

Recommended Growing Conditions :

RPMI 1640 + 15% FCS

Research Area :

Cancer, Virology

more info or order :

Ximbio product webpage