Anti-XPF [XPF 3F2/3] | Ximbio 151521 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-XPF [XPF 3F2/3]

catalog :

151521

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2072

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-XPF [XPF 3F2/3]

Catalogue Number :

151521

Applications :

ELISA IHC IF WB

Antigen/Gene or Protein Targets :

XPF

Reactivity :

Human

Relevance :

Nucleotide excision repair (NER) is a DNA repair pathway that removes lesions induced by a variety of agents such as UV irradiation. ERCC1 and XPF form the heterodimer ERCC1-XPF, forming a DNA endonuclease that is essential for the dual incision step of NER (cleaves 5' of the DNA lesion).

Host :

Mouse

Immunogen :

A recombinant His-tagged fragment of human XPF protein produced in E. coli

Subclass :

IgG1

Myeloma Used :

Sp2/0-Ag14

Recommended Growing Conditions :

DMEM + 5% FCS

Strain :

Balb/c

Research Area :

DNA Damage and Repair, Epigenetics & Nuclear Signalling

Notes :

For a negative control test, embed human cell lines in paraffin and section and stain exactly as one would do for human tissue. It is then possible to include verified XPF-defective cells in the experiment. See references for further details. XP2YO cells are readily available from public cell banks.

more info or order :

Ximbio product webpage