Anti-Keratin6 [LHK6] | Ximbio 151440 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Keratin6 [LHK6]

catalog :

151440

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3848

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, FACS

more info or order :

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product information

Name :

Anti-Keratin6 [LHK6]

Catalogue Number :

151440

Applications :

ELISA FACS IHC IF WB

Antigen/Gene or Protein Targets :

Keratin 6

Synonyms :

CK6A, CK6B, CK6C, CK6D, CK6E, Keratin Type II Cytoskeletal 6A, Keratin Type II Cytoskeletal 6B, Keratin Type II Cytoskeletal 6C, Keratin Type II Cytoskeletal 6D, Keratin Type II Cytoskeletal 6E, KRT6, KRT6A, KRT6B, KRT6C, KRT6D, KRT6E Human Entrez Gene ID 3853-KRT6A, 3854-KRT6B, 286887-KRT6C Human SwissProt P02538-KRT6A, P04259-KRT6B, P48668-KRT6C Human Unigene 700779 Human Gene Symbol KRT6A; KRT6B; KRT6C Human Chromosome Location 12q13.13; 12q13.13; 12q13.13

Reactivity :

Human and Mouse

Relevance :

Clone LHK6 recognizes a protein of 56kDa, identified as cytokeratin 6 (CK6). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratin 9 to 23) and on type II kerating (1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratins 6,16 and 17 are expressed in suprabasasl keratinocytes of wounded epidermis. Keratin 6 is found in acrosyringeal keratinocyes in normal skin. LHK6 is a very good marker for hyperproliferative keratinocytes.

Host :

Mouse

Immunogen :

11 amino aid sequence GSSTIKYTTTS of K6b C terminal

Subclass :

IgG2a kappa

Positive Control :

Tonsil or basal cell carcinoma

Molecular Weight (kDa) :

55-57

Myeloma Used :

Sp2/0-Ag14

Recommended Growing Conditions :

DMEM + 5% FCS

Research Area :

Cell Signaling & Signal Transduction

Notes :

Cellular Localization: Cytoplasmic Suggested Dilutions: Flow Cytometry (0.5-1ug/million cells); Immunofluorescence (0.5-1ug/ml); Immunohistology (Formalin-fixed) (0.1-0.2ug/ml for 30 min at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)

more info or order :

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