Anti-HLADR [BU43] | Ximbio 151438 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-HLADR [BU43]

catalog :

151438

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2703

reactivity :

human

application :

immunohistochemistry, immunoprecipitation, FACS, radioimmunoassay

more info or order :

Ximbio product webpage

product information

Name :

Anti-HLADR [BU43]

Catalogue Number :

151438

Applications :

FACS IHC IP RIA

Antigen/Gene or Protein Targets :

Human Leukocyte Antigen-DR locus (HLA-DR) associated invariant chain (CD74)

Synonyms :

CD74 Molecule; HLA-DR Antigens-Associated Invariant Chain; Gamma Chain Of Class II Antigens; Ia-Associated Invariant Chain; MHC HLA-DR Gamma Chain; DHLAG; P33; CD74 Antigen; Ia-GAMMA; HLADG

Reactivity :

Human

Relevance :

HLA-DR-associated invariant chain (CD74) plays a role in antigen presentation. In addition to its expression on antigen-presenting cells, CD74 is expressed by carcinomas of renal, lung, gastric, and thymic origin and by certain sarcomas. The restricted expression of CD74 by normal tissues and its very rapid internalization make CD74 an attractive therapeutic target for both cancer and immunologic diseases. It has also been shown to have value as a gastric carcinoma marker.

Host :

Mouse

Immunogen :

HFB1 plasmacytoid cell line

Subclass :

IgM

Myeloma Used :

NS0

Recommended Growing Conditions :

RPMI 1640 + 10% FCS

Strain :

Balb/c

Research Area :

Immunology

more info or order :

Ximbio product webpage