product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-CD19 [BU12]
catalog :
151429
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
930
reactivity :
human
application :
immunohistochemistry, immunoprecipitation, FACS
more info or order :
Ximbio product webpage
product information
Name :
Anti-CD19 [BU12]
Catalogue Number :
151429
Applications :
FACS IHC IP
Antigen/Gene or Protein Targets :
CD19
Synonyms :
CD19 Molecule; B-Lymphocyte Surface Antigen B4; T-Cell Surface Antigen Leu-12; Differentiation Antigen CD19; CD19 Antigen; CVID3; B4
Reactivity :
Human
Relevance :
CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. It is a single chain glycoprotein, present on the surface of normal and neoplastic B-cells. CD19 is expressed at an early stage by projenitor B-cells in bone marrow and during all stages of B-cell maturation. This antigen is lost upon terminal differentiation to plasma cells. CD19 is important for detecting both normal and neoplastic B-cells. CD19 is present on neoplasms arising from early B-cells (e.g. acute leukaemia of pre-B-cells) and more differentiated B-cell neoplasms (e.g. chronic Lymphocytic leukaemia and non-Hodgkin's lymphoma). Leukaemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen. The CD19 cytoplasmic domain binds tyrosine kinases and PI-3 kinase.
Host :
Mouse
Immunogen :
Human EB-4 Burkitt's lymphoma cell line
Subclass :
IgG1
Recommended Growing Conditions :
RPMI 1640 + 10% FCS
Strain :
Balb/c
Research Area :
Cancer, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology
Notes :
FACS dilution: 1/50 to 1/200
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com