product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-CD86 [BU63]
catalog :
151428
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
942
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS
more info or order :
Ximbio product webpage
product information
Name :
Anti-CD86 [BU63]
Catalogue Number :
151428
Applications :
FACS IHC IF IP WB
Antigen/Gene or Protein Targets :
CD86
Synonyms :
B7.2
Reactivity :
Human
Relevance :
CD86 is a 70 kDa type I transmembrane glycoprotein belonging to the immunoglobulin superfamily of cell surface receptors. CD86 is expressed on resting monocytes and dendritic cells, activated T and Natural Killer cells, and is rapidly induced on the surface of activated B-cells, suggesting that it is a major CD28 ligand and may play an important role for the co-stimulation of T-cells in the primary immune response. CD86 is also expressed by malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.
Host :
Mouse
Immunogen :
ARH 77 (B-lymphoblastoid cell line)
Subclass :
IgG1
Myeloma Used :
P3/NS1/1-Ag4.1
Recommended Growing Conditions :
RPMI 1640 + 10% FCS
Strain :
Balb/c
Research Area :
Cell Type or Organelle Marker, Immunology, Stem Cell Biology
Notes :
Recommended for the inhibition of the mixed lymphocyte reaction (MLR) and the binding of soluble CTLA-4 (CD152)-mulg fusion protein to CD 86 (B7-2). Western Blot 1:1000 Flow Cytometry 5 ug/ml Immunohistochemistry 1:10-1:2000 Immunohistochemistry-Frozen 1:200 Immunoprecipitation 1:50
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com