Anti-HSP27 [ACD5] | Ximbio 151427 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-HSP27 [ACD5]

catalog :

151427

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3315

reactivity :

human

application :

immunohistochemistry, immunoprecipitation

more info or order :

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product information

Name :

Anti-HSP27 [ACD5]

Catalogue Number :

151427

Applications :

IHC IP

Antigen/Gene or Protein Targets :

HSP27

Synonyms :

Heat Shock Protein Family B (Small) Member 1; Estrogen-Regulated 24 KDa Protein; Stress-Responsive Protein 27; Heat Shock 27kDa Protein; HSP27; HSP28; SRP27; Epididymis Secretory Protein Li 102; HEL-S-102; HS.76067; CMT2F; HMN2B; Hsp25; HspB1

Reactivity :

Human

Relevance :

The anti estrogen receptor (RE) antibody ACD5 (also known as D5) is capable of precipitating labelled human cytosolic RE complexes from breast tumour, fibroid, myometrial and endometrial preparations, but does not react with nuclear RE from human endometrium or cytoplasmic RE from other species tested. The antibody does not react with progesterone receptor or androgen receptor from human breast tissue, sex steroid binding globulin (SHBG) from human plasma, or rat alpha fetoprotein. The antibody is associated with a 29KDa component in RE-positive cytosols, in addition the antigen is a non hormone binding component related to cytosolic RE from breast tumour and myometrium.

Host :

Mouse

Immunogen :

Purified cytoplasmic oestrogen receptor fragment from human myometrium.

Subclass :

IgG1

Molecular Weight (kDa) :

Myeloma Used :

P3X63Ag8.653

Recommended Growing Conditions :

RPMI + 20% FCS, penicillin 100 (units/ml), streptomycin (100ug/ml)

Strain :

Balb/c

Research Area :

Cancer, Cardiovascular, Cell Signaling & Signal Transduction

Notes :

Since publication of the Coffer et al 1985 paper, work has been performed to elucidate the nature of the 29KDa protein. It is an abundant protein that had previously been discussed under three different names, p29, p24 and srp27, but it is known that they are one and the same protein and now called Heat Shock Protein 27, HSP27.

more info or order :

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