Anti-BCL2 [bcl-2/124] | Ximbio 151407 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-BCL2 [bcl-2/124]

catalog :

151407

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

596

reactivity :

human

application :

western blot, immunohistochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-BCL2 [bcl-2/124]

Catalogue Number :

151407

Applications :

IHC WB

Antigen/Gene or Protein Targets :

Bcl2

Reactivity :

Human

Relevance :

The pro-survival protein BCL2 derives its name from B-cell lymphoma 2, as it is the second member of a range of proteins initially described in chromosomal translocations involving chromosomes 14 and 18 in follicular lymphomas. Damage to the Bcl-2 gene has been identified as a cause of a number of cancers, including melanoma, breast, prostate, chronic lymphocytic leukemia, and lung cancer, and a possible cause of schizophrenia and autoimmunity. It is also a cause of resistance to cancer treatments.

Host :

Mouse

Immunogen :

Synthetic peptide of amino acids 41-54 of human bcl-2 oncoprotein

Subclass :

IgG1

Myeloma Used :

P3/NS1/1-Ag4.1

Recommended Growing Conditions :

RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT

Research Area :

Apoptosis and Programmed Cell Death, Cancer, Cell Signaling & Signal Transduction, Metabolism

more info or order :

Ximbio product webpage