Anti-Spectrin [RG/26] | Ximbio 151403 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Spectrin [RG/26]

catalog :

151403

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6709

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-Spectrin [RG/26]

Catalogue Number :

151403

Applications :

IHC IF IP WB

Antigen/Gene or Protein Targets :

Spectrin

Reactivity :

Human

Relevance :

Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane of many cell types in pentagonal or hexagonal arrangements, forming a scaffolding and playing an important role in maintenance of plasma membrane integrity and cytoskeletal structure. In certain types of brain injury such as diffuse axonal injury, spectrin is irreversibly cleaved by the proteolytic enzyme calpain, destroying the cytosketelon. Spectrin cleavage causes the membrane to form blebs and ultimately to be degraded, usually leading to cell death.

Host :

Mouse

Immunogen :

Red cell membranes

Subclass :

IgG2a

Myeloma Used :

P3/NS1/1-Ag4.1

Recommended Growing Conditions :

RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT

Research Area :

Cardiovascular, Neurobiology, Protein Degradation

Notes :

Ultroser G can be used at 1% if the cells are not growing well.

more info or order :

Ximbio product webpage