Anti-CD79b [B29/123] | Ximbio 151376 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-CD79b [B29/123]

catalog :

151376

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

974

reactivity :

human

application :

western blot, immunohistochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-CD79b [B29/123]

Catalogue Number :

151376

Applications :

IHC WB

Antigen/Gene or Protein Targets :

CD79b

Synonyms :

CD79b Molecule; CD79B Antigen (Immunoglobulin-Associated Beta); Immunoglobulin-Associated B29 Protein; B-Cell-Specific Glycoprotein B29; Ig-Beta

Reactivity :

Human

Relevance :

The B-cell Antigen receptor constitutes a disulphide linked heterodimer, consisting of CD79a (mb1) and CD79b / B29 polypeptides which are non-covalently associated with membrane bound immunoglobulins on B-cells. CD79a first appears at pre B-cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in B-cell lymphomas, in B-cell lines, the majority of acute leukemias of precursor B-cell type and in some myelomas. The CD79a/b heterodimer interacts with at least one tyrosine kinase (Lyn). The induction of tyrosine kinase activity after antigen binding leads to phosphorylation of the CD79a/b dimer, and also of other molecules, thereby initiating intracellular signalling.

Host :

Mouse

Immunogen :

Synthetic peptide representing the c-terminus from residue 215 of the murine B29 polypeptide.

Subclass :

IgG2b

Myeloma Used :

P3/NS1/1-Ag4.1

Recommended Growing Conditions :

RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT

Research Area :

Cell Signaling & Signal Transduction, Immunology

Notes :

Ultroser G can be used at 1% if the cells are not growing well.

more info or order :

Ximbio product webpage