Anti-CD45RB [PD7/26] | Ximbio 151364 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-CD45RB [PD7/26]

catalog :

151364

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-CD45RB [PD7/26]

Catalogue Number :

151364

Applications :

FACS IHC IF WB

Antigen/Gene or Protein Targets :

Protein tyrosine phosphatase, receptor type, C (PTPRC, CD45RB)

Synonyms :

Protein Tyrosine Phosphatase; Receptor Type C; CD45 Antigen; CD45; L-CA; T200; Protein Tyrosine Phosphatase; Receptor Type; C Polypeptide; T200 Leukocyte Common Antigen; T200 Glycoprotein; EC 3.1.3.48; GP180; CD45R; B220; LCA; LY5

Reactivity :

Human

Relevance :

PTPRC (CD45) is a transmembrane tyrosine phosphatase that is present on all leukocytes. PTPRC regulates the threshold of T cell antigen receptor (TCR) signaling through dephosphorylation of protein tyrosine kinases (e.g. Lck and Fyn). CD45RB is an isoform of the PTPRC (CD45) protein which is expressed on peripheral B cells, T cytotoxic cells and CD4+ T cells. It has a role in cell signalling regulation through the activation of the Src family of tyrosine kinases. PD7/26 is widely used, in conjunction the CD45 antibody 2B11, to detect white cell-derived tumours in paraffin sections.

Host :

Mouse

Immunogen :

Human PBL maintained in T-cell growth factor

Subclass :

IgG1

Myeloma Used :

P3/NS1/1-Ag4.1

Recommended Growing Conditions :

RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT

Research Area :

Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology

Notes :

Ultroser G can be used at 1% if the cells are not growing well.

more info or order :

Ximbio product webpage