product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-PTPRC [2B11]
catalog :
151361
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
52
reactivity :
human
application :
western blot, immunohistochemistry, FACS
more info or order :
Ximbio product webpage
product information
Name :
Anti-PTPRC [2B11]
Catalogue Number :
151361
Applications :
FACS IHC WB
Antigen/Gene or Protein Targets :
Protein tyrosine phosphatase, receptor type, C (PTPRC, CD45)
Synonyms :
Protein Tyrosine Phosphatase; Receptor Type C; CD45; L-CA; T200; Protein Tyrosine Phosphatase; Receptor Type; C Polypeptide; T200 Leukocyte Common Antigen; Leukocyte Common Antigen; T200 Glycoprotein; GP180; CD45R; B220; LCA; LY5
Reactivity :
Human
Relevance :
PTPRC is a transmembrane tyrosine phosphatase that is present on all leukocytes. PTPRC regulates the threshold of T cell antigen receptor (TCR) signaling through dephosphorylation of protein tyrosine kinases (e.g. Lck and Fyn). 2B11 is widely used, in conjunction with the CD45RB antibody PD7/26, to detect white cell-derived tumours in paraffin sections.
Host :
Mouse
Immunogen :
T cell Lymphoma cells
Subclass :
IgG1 kappa
Myeloma Used :
P3/NS1/1-Ag4.1
Recommended Growing Conditions :
RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
Research Area :
Cardiovascular, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Immunology, Neurobiology, Stem Cell Biology
Notes :
Ultroser G can be used at 1% if the cells are not growing well.
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com