Anti-SIGLEC2 [TPD44/D11] | Ximbio 151356 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-SIGLEC2 [TPD44/D11]

catalog :

151356

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

29115

reactivity :

human

application :

immunohistochemistry, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-SIGLEC2 [TPD44/D11]

Catalogue Number :

151356

Applications :

FACS IHC

Antigen/Gene or Protein Targets :

Sialic acid binding Ig-like lectin 2 (SIGLEC2, CD22, BL-CAM)

Synonyms :

CD22 Antigen; Sialic Acid Binding Ig-Like Lectin 2; B-Lymphocyte Cell Adhesion Molecule; T-Cell Surface Antigen Leu-14; SIGLEC-2; BL-CAM

Reactivity :

Human

Relevance :

SIGLEC-2 (CD22) is first expressed in the cytomplasm of pre- and pro- B cells. SIGLEC-2 is broadly expressed in normal and neoplastic B cells and absent from other leucocytes and tissues. SIGLEC-2 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation. SIGLEC-2 is strongly expressed in hairy cell leukaemias.

Host :

Mouse

Immunogen :

B cell lymphoma cells

Subclass :

IgG2a

Myeloma Used :

P3/NS1/1-Ag4.1

Recommended Growing Conditions :

RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT

Research Area :

Cancer, Immunology, Stem Cell Biology

Notes :

Ultroser G can be used at 1% if the cells are not growing well.

more info or order :

Ximbio product webpage