Anti-CD19 [PDR134] | Ximbio 151352 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-CD19 [PDR134]

catalog :

151352

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

930

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-CD19 [PDR134]

Catalogue Number :

151352

Applications :

FACS IHC IF IP WB

Antigen/Gene or Protein Targets :

CD19

Synonyms :

CD19 Molecule; B-Lymphocyte Surface Antigen B4; T-Cell Surface Antigen Leu-12; Differentiation Antigen CD19; CD19 Antigen; CVID3; B4

Reactivity :

Human

Relevance :

CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. It is a single chain glycoprotein, present on the surface of normal and neoplastic B-cells. CD19 is expressed at an early stage by progenitor B-cells in bone marrow and during all stages of B-cell maturation. This antigen is lost upon terminal differentiation to plasma cells. CD19 is important for detecting both normal and neoplastic B-cells. CD19 is present on neoplasms arising from early B-cells (e.g. acute leukemia of pre-B-cells) and more differentiated B-cell neoplasms (e.g. chronic lymphocytic leukemia and non-Hodgkin’s lymphoma). Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen. The CD19 cytoplasmic domain binds tyrosine kinases and PI-3 kinase.

Host :

Mouse

Immunogen :

Pokeweek-stimulated Daudi and Raji cells

Subclass :

IgM

Myeloma Used :

P3/NS1/1-Ag4.1

Recommended Growing Conditions :

RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT

Research Area :

Cancer, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology

Notes :

Ultroser G can be used at 1% if the cells are not growing well.

more info or order :

Ximbio product webpage